Kissan Fresh* Tomato Ketchup is made with 100% real, naturally ripened Tomatoes. Ketchup is made with tomatoes, sugar, vinegar/acetic acid and spices. Whereas, tomato sauce is made from tomatoes, oil, meat or vegetable stock and spices. It never uses vinegar. … To make it simpler, ketchup is made with a variety of spices while the sauce is generally made without spices